The demand for squalene oil in the USA is witnessing steady growth, driven by rising applications across cosmetics, pharmaceuticals, nutraceuticals, and emerging biotech formulations. As consumers shift toward high-performance, natural, and sustainable ingredients, squalene has become an essential component due to its excellent moisturizing, antioxidant, emollient, and skin-repairing properties. The market is also benefiting from increasing awareness of clean-label cosmetic ingredients, evolving skincare routines, and strong investments in plant-based squalene production technologies.
Quick Stats for USA Squalene Oil Industry
- USA Squalene Oil Sales Value (2025): USD 125.70 million
- USA Squalene Oil Forecast Value (2035): USD 227.50 million
- USA Squalene Oil Forecast CAGR: 6.20%
- Leading Source in USA Squalene Oil Industry: Plant-based (Olive, Amaranth) (67.50%)
- Key Growth Regions in USA Squalene Oil Industry: West, Northeast, South, Midwest
- Regional Leadership: West holds the leading position in demand
- Key Players in USA Squalene Oil Industry: Croda International Plc, Amyris Inc., SEPPIC S.A., BASF Corporation, Bosk Bioproducts LLC, Evonik Industries AG, Gattefossé Corporation, Sophim S.A.S., Clariant Corporation, Hallstar Company
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Market Overview
Squalene oil, a naturally occurring polyunsaturated hydrocarbon, is extracted from plant sources such as olives, amaranth seeds, sugarcane, and rice bran. Historically obtained from shark liver, the industry has now pivoted toward plant-derived and bio-fermented alternatives due to regulatory limitations and sustainability concerns.
In the USA, the squalene market is being reformulated around ethical production, clean beauty trends, and high consumption of premium skincare. Its strong presence in anti-aging creams, serums, moisturizers, and pharmaceutical formulations continues to fuel widespread adoption.
Key Factors Driving Demand
1. Rising Use in Cosmetics and Personal Care
Cosmetic manufacturers in the USA are increasing the use of squalene due to its ability to replicate natural skin lipids and improve moisture retention.
Key drivers include:
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Growing demand for premium moisturizers and anti-aging products
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Rising preference for natural and non-comedogenic oils
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Increasing male grooming trends and specialty skincare
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Expanding retail distribution via e-commerce and beauty stores
Squalene-based products are often marketed for their luxuriously light texture, fast absorption, and compatibility with sensitive skin, which enhances market penetration.
2. Increased Application in Pharmaceuticals
Squalene is widely used as an adjuvant in vaccine formulations to boost immune response. Pharmaceutical companies in the USA are integrating squalene into novel drug-delivery systems, immunotherapies, and nutraceutical formulations.
Growth contributors:
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Advancements in vaccine R&D
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Increased investment in immunology
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Rising preference for natural adjuvants
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Regulatory acceptance of plant-derived squalene in pharma
3. Shift Toward Sustainable and Plant-Based Sources
Sustainability concerns have significantly transformed the squalene supply landscape.
Key trends include:
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Rise of sugarcane-derived and olive-derived squalene
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Increasing demand for vegan and cruelty-free ingredients
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Strong regulatory push against shark-based squalene
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Rising biotechnology innovations in bio-fermented squalene
US brands are highly committed to ethical sourcing, making sustainability a central market driver.
4. Growth in Nutraceuticals and Functional Health Products
Squalene’s antioxidant and cellular-repair properties make it useful in dietary supplements promoting skin health, immunity, and metabolism.
Demand is rising due to:
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Consumer focus on holistic wellness
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Popularity of antioxidant-rich supplements
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Growing acceptance of natural oils in nutrition
Market Challenges
Despite the rising demand, certain challenges influence growth patterns:
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High production cost of plant-based squalene
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Limited availability of raw materials such as premium-grade olive oil
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Risk of supply chain disruptions in agriculture-based sourcing
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Intense competition from alternative emollients
Nonetheless, strong R&D investments continue to resolve these limitations.
Emerging Opportunities
The USA squalene oil market is positioned for strong expansion due to multiple opportunities such as:
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Development of biotechnological fermentation-based squalene
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Increasing adoption in luxury cosmetic brands
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Rising use in nanotechnology-based drug delivery systems
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Expansion of vegan skincare and clean beauty startups
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Pharmaceutical demand for next-gen vaccine adjuvants
Future Outlook
The future of squalene oil in the USA appears promising as manufacturers continue to adopt eco-friendly, non-animal extraction techniques. With rapid advancements in biotechnology, domestic production is expected to increase, reducing reliance on imports and stabilizing costs. Cosmetic and pharmaceutical applications will continue to dominate the market, while nutraceuticals and functional skincare further expand demand.
Growing awareness of skin health, rising disposable income, and the shift toward natural ingredients will ensure that squalene remains a highly sought-after multifunctional ingredient across industries.
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